Complications of Mechanical Ventilation
Mechanical ventilation, while lifesaving, is associated with several complications involving respiratory system, gastrointestinal system, cardiovascular system, and overall patient outcomes.
1. Infection – Ventilator-Associated Pneumonia (VAP):
- Usually develops more than 48 hours of mechanical ventilation.
- Clinical features include fever, increased secretions, and a change in the color or odor of sputum.
2. Barotrauma
- Caused by excessive airway pressure
- May result in alveolar rupture and pneumothorax (collection of air between the pleura and lung).
- Signs include sudden drop in SpO₂, decreased or absent breath sounds, and respiratory distress.
- Severe cases can lead to tension pneumothorax (life-threatening emergency).
3. Volutrauma
- Caused by high tidal volume.
- Leads to alveolar overdistension and collapse.
4. Alveolar Collapse (Atelectasis)
- May occur due to inadequate ventilation, mucus plugging, or inappropriate ventilator settings.
- Results in impaired oxygen exchange.
- Prevention: recruitment maneuvers, adequate PEEP (positive end-expiratory pressure), and suctioning.
5. Hypoventilation and Hyperventilation
- Hypoventilation: insufficient ventilation, can lead to hypercapnia (High PaCO₂).
- Hyperventilation: excessive ventilatio, can lead to hypocapnia (Low PaCO₂).
- Both can lead to acid–base imbalance and altered patient outcomes.
6. Patient–Ventilator Asynchrony
- Mismatch between patient effort and ventilator.
- Increases work of breathing and discomfort.
7. Stress Ulcers (Gastrointestinal Complication)
- Common in critically ill patients.
- Stress Ulcers c an cause GI bleeding.
- Prevent with H₂ blockers (Ranitidine) or PPIs (Pantoprazole).
8. Respiratory Muscle Weakness and Atrophy
- Prolonged ventilation can cause diaphragm and muscle atrophy.
- Can make weaning from the ventilator difficult.
9. Cardiovascular Complications
- Positive pressure ventilation increases intrathoracic pressure.
- This reduces venous return (preload) causing decreased cardiac output leading to hypotension.
- Patients with hypovolemia or cardiac dysfunction are more vulnerable.
Nursing Care
To prevent infection
- HOB elevation at a minimum of 30 to 45 degrees
- No routine changes of the patient’s ventilator circuit tubing
- Strict hand washing & using sterile gloves always
To reduce secretion
- Assess for the presence of secretions by lung auscultation at least every 2 to 4 hours
- Turn the patient every 1 to 2 hours,
- Providing chest physiotherapy to lung areas with increased secretions
- Suctioning:
- Not required routinely as it can damage the airway mucosa
- Suction only when there is excess secretions
Managing alarms
- If,at any time, the ventilator is malfunctioning (e.g., failure of O2 supply)
- Disconnect the patient from the machine
- Manually ventilate with a BVM and 100% O2 until the ventilator is fixed
Ventilator asynchrony
- If a patient breathes out of synchrony due to anxiety or pain, sit with the patient and verbally coach them to breathe with the ventilator.
- Paralyze the patient with a neuromuscular blocking agent to provide more effective synchrony, as advised
- Remember that the paralyzed patient can hear, see, think, and feel. It is very important to administer IV sedation and analgesia concurrently when the patient is paralyzed.
- Restraints always come last.
- Although appearing to be asleep, sedated, or paralyzed, always address them as if they were awake and alert
ETcO2 (Capnography)
- End-tidal carbon dioxide monitoring
- Used for confirmation of ET tube placement & ventilation
- Normal CO2 value – 35-45mmHg
- >45 – Hypoventilation
- <35 – Hyperventilation